Viruses can be differentiated based on how they store their genomic information, such as by DNA or doublestranded RNA Positivesense singlestranded RNA (ssRNA) viruses are one such way and itSubsequent studies have detected virusderived small RNAs and RNAbased antiviral immunity in fungi, plants, D melanogaster, mosquitoes, silkworms and C elegans The target viruses have many different types of genome, including ()RNA, negativestrand RNA ((–)RNA), dsRNA, singlestranded DNA (ssDNA) and dsDNA (TABLE 1) An early study failedMRNA endonucleolytically 10–13 nucleotides from the 5′ end and utilizes the capped fragment as a primer to synthesize viral transcripts Here we report a unique capsnatching mechanism by which the yeast doublestranded RNA totivirus LA furnishes its transcript with a cap structure derived from mRNA Unlike influen
The Viruses General Microbiology
